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Results Glutathione depletion vulnerability Glutathione is suggested to be the dominant coordinating ligand for cytosolic ferrous iron (Hider and Kong, 2011) and is also the substrate used by glutathione peroxidase-4 (GPX4) to clear the lipid peroxides that induce ferroptotic cell death (Dixon and Stockwell, 2014

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In addition, researchers continue to investigate its influence on immune cell function, inflammatory signaling, and cellular communication, making glutathione an important research tool across immunology and regenerative biology